With subjective experience new cells are incorporated into the brain and new circuits are created, altered, strengthened or weakened. The static view of the brain has been disproven and it is now known that the brain is very active—constantly changing connections and growing circuits, thought-by-thought, minute-by-minute and day-by-day. Many different brain mechanisms alter neuronal connections—in large networks, not just in individual synapses. In fact, the larger the brain circuit involved in the neuroplasticity, the better the learning and the more powerful the experience. This neuroplasticity primer and update includes important examples of mental events changing brain circuits.